Document 0655
 DOCN  M9480655
 TI    [A new prophylactic agent in AIDS: Ansatipine. Disseminated
       Mycobacterium avium complex infection is now the most frequent of the
       opportunistic bacterial infections in AIDS]
 DT    9410
 AU    Dautzenberg B; Service des Maladies Respiratoires, Groupe Hospitalier
       Pitie-; Salpetriere, Paris.
 SO    Allerg Immunol (Paris). 1994 Apr;26(4):141-4. Unique Identifier :
       AIDSLINE MED/94304496
 AB    Otherwise infrequent, infections by non-tuberculous or atypical
       mycobacteria are now rising in AIDS. Infection with the Mycobacterium
       avium complex (MAC) is now the most frequent opportunistic bacterial
       infection, because of better detection of HIV positive patients. The
       incidence, which is probably underestimated, is now 14-33% in France.
       The Mycobacterium avium complex is responsible for 96% of infections by
       atypical mycobacteria in AIDS patients. Diagnosis of infection by MAC is
       bacteriological. The clinical picture is non-specific and associates
       high fever, profuse sweating, weight loss and asthenia, all of which
       make a severe alteration to the general condition. This infection
       persists in AIDS patients to a late phase of evolution where
       Immunodeficiency is profound, that is when the level of CD4 lymphocytes
       is low. Because of this, it is an increasing and preoccupying problem in
       patients, since it involves the prognosis of life. This shows the
       importance of prophylactic treatment for this pathology.
 DE    AIDS-Related Opportunistic Infections/*EPIDEMIOLOGY/MICROBIOLOGY/
       PREVENTION & CONTROL  English Abstract  France/EPIDEMIOLOGY  Human
       Incidence  Mycobacterium avium-intracellulare Infection/*EPIDEMIOLOGY/
       PREVENTION & CONTROL  Rifabutin/*THERAPEUTIC USE  United
       States/EPIDEMIOLOGY  JOURNAL ARTICLE

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